Procedural recommendations of cardiac PET/CT imaging: standardization in inflammatory-, infective-, infiltrative-, and innervation (4Is)-related cardiovascular diseases: a joint collaboration of the EACVI and the EANM

• DOI: 10.1007/s00259-020-05066-5
• Publication Date: 2020-10-27T03:03:00Z
• Authors: Riemer H. J. A. S...; Andor W. J. M. Gl...; Olivier Gheysens; Mark Lubberink; Tanja Kero; Marc R. Dweck; Gilbert Habib; Oliver Gaemperli; Antti Saraste; Alessia Gimelli; Panagiotis Georgo...; Hein J. Verberne; Jan Bucerius; Christoph Rischpler; Fabien Hyafil; Paola A. Erba
• Keywords: PET/CT; [SDV]Life Sciences [q-bio]; Medizin; Procedural recommendations; 610; Guidelines; 03 medical and health sciences; 0302 clinical medicine; Eacvi/Eanm Recommendation; Fluorodeoxyglucose F18; Positron Emission Tomography Computed Tomography; Humans; Cardiac PET/CT • Joined procedurals • 4Is • cardiovascular diseases; 10. No inequality; [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology; [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases; 2. Zero hunger; 4Is; Cardiovascular diseases; PET/CT; Procedural recommendations;; 4Is; Cardiovascular diseases; PET/CT; Procedural recommendations; Reference Standards; 4Is; Cardiac PET/CT; Cardiovascular diseases; Joined procedurals;; [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system; 3. Good health; [SDV] Life Sciences [q-bio]; 4Is; Cardiovascular diseases; Cardiovascular Diseases; Positron-Emission Tomography; [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases; Radiologi och bildbehandling; [SDV.MP.BAC] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology; Radiopharmaceuticals; Tomography, X-Ray Computed; [SDV.MP.PAR] Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology; Radiology, Nuclear Medicine and Medical Imaging

AbstractWith this document, we provide a standard for PET/(diagnostic) CT imaging procedures in cardiovascular diseases that are inflammatory, infective, infiltrative, or associated with dysfunctional innervation (4Is). This standard should be applied in clinical practice and integrated in clinical (multicenter) trials for optimal procedural standardization. A major focus is put on procedures using [18F]FDG, but 4Is PET radiopharmaceuticals beyond [18F]FDG are also described in this document. Whilst these novel tracers are currently mainly applied in early clinical trials, some multicenter trials are underway and we foresee in the near future their use in clinical care and inclusion in the clinical guidelines. Finally, PET/MR applications in 4Is cardiovascular diseases are also briefly described. Diagnosis and management of 4Is-related cardiovascular diseases are generally complex and often require a multidisciplinary approach by a team of experts. The new standards described herein should be applied when using PET/CT and PET/MR, within a multimodality imaging framework both in clinical practice and in clinical trials for 4Is cardiovascular indications.