EANM practice guideline for quantitative SPECT-CT

• DOI: 10.1007/s00259-022-06028-9
• Publication Date: 2022-12-05T07:03:02Z
• Authors: John C. Dickson; Ian S. Armstrong; Pablo Minguez Gabiña; Ana M. Denis-Bacelar; Aron K. Krizsan; Jonathan M. Gear; Tim Van den Wyngaert; Lioe-Fee de Geus-Oei; Ken Herrmann
• Keywords: Computer. Automation; Diagnostic Imaging; Radioisotopes; Single Photon Emission Computed Tomography Computed Tomography; dosimetry; neurology; Medizin; Cardiology; Guidelines; bone; quantification; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Neurology; SPECT-CT; Quantification; Dosimetry; cardiology; Humans; Human medicine; Nuclear Medicine; Bone; Radionuclide Imaging

Abstract PurposeQuantitative SPECT-CT is a modality of growing importance with initial developments in post radionuclide therapy dosimetry, and more recent expansion into bone, cardiac and brain imaging together with the concept of theranostics more generally. The aim of this document is to provide guidelines for nuclear medicine departments setting up and developing their quantitative SPECT-CT service with guidance on protocols, harmonisation and clinical use cases.MethodsThese practice guidelines were written by members of the European Association of Nuclear Medicine Physics, Dosimetry, Oncology and Bone committees representing the current major stakeholders in Quantitative SPECT-CT. The guidelines have also been reviewed and approved by all EANM committees and have been endorsed by the European Association of Nuclear Medicine.ConclusionThe present practice guidelines will help practitioners, scientists and researchers perform high-quality quantitative SPECT-CT and will provide a framework for the continuing development of quantitative SPECT-CT as an established modality.