Prospective Clinical Trial for Predicting Mastectomy Skin Flap Necrosis with Indocyanine Green Angiography in Implant-Based Prepectoral Breast Reconstruction

Indocyanine Green
DOI: 10.1007/s00266-024-04106-x Publication Date: 2024-05-13T20:23:31Z
ABSTRACT
Abstract Background Indocyanine green angiography (ICG-A) is a useful tool for evaluating mastectomy skin flap (MSF) perfusion during breast reconstruction. However, standardized protocol interpreting and applying MSF after has not been established yet. The purpose of this study to establish criteria assessing in immediate implant-based prepectoral reconstruction while correlating ICG-A findings with postoperative outcomes Methods This prospective observational was conducted at single institution involved patients cancer who underwent between August 2021 2023. terms “hypoperfused flap” area” were defined according perfusion. exhibited < 30% perfusion, excluding the nipple corresponding region, respectively. Data on hypoperfused flap, area, necrosis collected. Results Fifty-three cases analyzed. Eight developed (15.1%, 8/53). Of these, two surgical debridement revision within 3 months (3.8%, 2/53). There nine eight which necrosis. significant predictor occurrence ( p 0.001). tendency increased full-thickness wider area. Conclusions enabled prediction high sensitivity, specificity, positive predictive value, negative value. Considering presumed correlation extent area need surgery, caution should be exercised when making intraoperative decisions regarding method. Level Evidence III journal requires that authors assign level evidence each article. For full description these Evidence-Based Medicine ratings, please refer Table Contents or online Instructions Authors www.springer.com/00266 .
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