Prevalence and outcomes of end-stage kidney disease in patients with systemic lupus erythematous: a population-based study

• DOI: 10.1007/s00296-023-05409-z
• Publication Date: 2023-08-14T20:04:16Z
• Authors: Chunhuan Lao; Philippa Van Dantzig; Douglas White; Kannaiyan Rabindr...; Donna Foxall; Ross Lawrenson
• Keywords: Nephrology

Abstract This study aims to examine the prevalence and outcomes of end-stage kidney disease (ESKD) among systemic lupus erythematosus (SLE) patients. SLE patients identified from national administrative datasets were linked Australia New Zealand Dialysis Transplant Registry (ANZDATA) identify ESKD cases. Period was calculated. The risk developing by ethnicity explored with Cox Proportional Hazards model. adjusted hazard ratio (HR) all-cause mortality for Māori, Pacific, Asian compared European/others estimated. Of 2837 patients, 210 (7.4%) developed ESKD. average period 5.7%. Men had twice rate than women (10.0% vs 5.2%). Māori Pacific higher (9.4%, 9.8% 4.4% 3.8%). HR men 3.37 (95% CI 1.62–7.02). 4.63 1.61–13.29) 4.66 1.67–13.00), respectively. Compared European/others, an 2.17 1.18–4.00) mortality. a high Men, more likely develop poorer survival other Interventions are needed reduce improve disadvantaged groups.