Breast MR biopsy: Pathological and radiological correlation

• DOI: 10.1007/s00330-015-4071-y
• Publication Date: 2015-10-28T23:41:18Z
• Authors: Chloé Dratwa; Aurélie Jalaguier...; Jeanne Thomassin-...; Julie Gonin; Jocelyne Chopier; Martine Antoine; Isabelle Trop; Emile Darai; Isabelle Thomassi...
• Keywords: Adult; Image-Guided Biopsy; Biopsy, Needle; Breast Neoplasms; Middle Aged; Magnetic Resonance Imaging; 3. Good health; Young Adult; 03 medical and health sciences; Carcinoma, Intraductal, Noninfiltrating; 0302 clinical medicine; Humans; Female; Breast; Aged; Retrospective Studies

To identify pathological features for sample analysis of magnetic resonance imaging-guided vaccum-assisted breast biopsy (MRIgVaBB) to optimize radio pathological correlation and identify discordant benign result.Databases of two centres were queried to identify MRIgVaBB performed between January 2009 and February 2013. A cohort of 197 women (mean age: 54.5 years (24-77)) with 208 lesions was identified. We retrospectively analyzed all prebiopsy MRI examinations according to the new BI-RADS lexicon, and all biopsy samples to describe the lesion of interest, its interface with the surrounding breast tissue and other associated features.The malignancy rate was 26.0 % (54/208) with an underestimation rate of 15.67 % (5/32). A visible interface at pathology between a biopsied lesion and the surrounding breast tissue was more frequently identified in mass enhancement compared to NME or focus (p = 0.0003). Regional NME was correlated with a high degree of fibrosis (p = 0.001) and the presence of PASH (p = 0.0007). Linear or segmental NME was correlated with the presence of periductal mastitis (p = 0.0003).The description of a visible interface between the target lesion and the surrounding tissue is crucial to confirm the correct targeting of an MR mass or a NME.• Pathological interface correlated with magnetic resonance mass and focal non-mass enhancement (NME). • Linear or segmental NME correlated with mastitis or ductal carcinoma in situ. • Fibrosis and pseudoangiomatous stromal hyperplasia (PASH) are correlated with regional NME.