Do quantitative and qualitative shear wave elastography have a role in evaluating musculoskeletal soft tissue masses?

• DOI: 10.1007/s00330-016-4427-y
• Publication Date: 2016-06-08T08:17:44Z
• Authors: B. Pass; M. Jafari; E. Rowbotham; E. M. A. Hensor; H. Gupta; P. Robinson
• Keywords: Adult; Aged, 80 and over; Male; Biopsy; Reproducibility of Results; Sarcoma; Soft Tissue Neoplasms; Liposarcoma; Middle Aged; Glomus Tumor; Sensitivity and Specificity; 3. Good health; Molecular Weight; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Radiology Nuclear Medicine and imaging; Ultrasound; Elasticity Imaging Techniques; Humans; Female; Ultrasonography, Doppler, Color; Aged; Ultrasonography

To determine if quantitative and qualitative shear wave elastography have roles in evaluating musculoskeletal masses.105 consecutive patients, prospectively referred for biopsy within a specialist sarcoma centre, underwent B-mode, (m/s) (colour map) elastography. Reference was histology from subsequent or excision where possible. Statistical modelling performed to test data and/or B-mode imaging predicting malignancy.Of 105 masses, 39 were malignant 6 had no but benign characteristics at 12 months. Radiologist agreement moderate excellent Kw 0.52-0.64; PABAKw 0.85-0.90). B-Mode 78.8% specificity, 76.9% sensitivity malignancy. Quantitatively, adjusting age, lesion volume there statistically significant association between longitudinal velocity malignancy (OR [95% CI] 0.40[0.10, 1.60], p=0.193), some evidence that higher transverse associated with decreased odds of (0.28[0.06, 1.28], p=0.101). Qualitatively masses tended be towards the blue spectrum (lower velocities); 39.5% (17/43) predominantly malignant, compared 14.3% (1/7) red lesions.Quantitatively qualitatively is There clear additional role currently.• Correlation soft tissue insignificant • ultrasound 76.9 % sensitive 78.8 specific models show does not significantly add assessment.