Expert consensus on oncological [18F]FDG total-body PET/CT imaging (version 1)

• DOI: 10.1007/s00330-022-08960-8
• Publication Date: 2022-06-25T06:02:41Z
• Authors: Haojun Yu; Yushen Gu; Wei Fan; Yongju Gao; Meiyun Wang; Xiaohua Zhu; Zhifang Wu; Jianjun Liu; Biao Li; Hubing Wu; Zhaoping Cheng; Shuxia Wang; Yiqiu Zhang; Baixuan Xu; Sijin Li; Hongcheng Shi
• Keywords: 03 medical and health sciences; Consensus; Tomography Scanners, X-Ray Computed; 0302 clinical medicine; Fluorodeoxyglucose F18; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Humans; Radiopharmaceuticals

[18F]FDG imaging on total-body PET/CT (TB PET/CT) scanners, with improved sensitivity, offers new potentials for cancer diagnosis, staging, and radiation treatment planning. This consensus provides the protocols for clinical practices with a goal of paving the way for future studies with the total-body scanners in oncological [18F]FDG TB PET/CT imaging.The consensus was summarized based on the published guidelines and peer-reviewed articles of TB PET/CT in the literature, along with the opinions of the experts from major research institutions with a total of 40,000 cases performed on the TB PET/CT scanners.This consensus describes the protocols for routine and dynamic [18F]FDG TB PET/CT scanning focusing on the reduction of imaging acquisition time and FDG injected activity, which may serve as a reference for research and clinic oncological PET/CT studies.This expert consensus focuses on the reduction of acquisition time and FDG injected activity with a TB PET/CT scanner, which may improve the patient throughput or reduce the radiation exposure in daily clinical oncologic imaging.• [18F]FDG-imaging protocols for oncological total-body PET/CT with reduced acquisition time or with different FDG activity levels have been summarized from multicenter studies. • Total-body PET/CT provides better image quality and improved diagnostic insights. • Clinical workflow and patient management have been improved.