Epidemiology of hypospadias in Europe: a registry-based study

• DOI: 10.1007/s00345-015-1507-6
• Publication Date: 2015-02-24T07:32:39Z
• Authors: Jorieke E. H. Ber...; Maria Loane; Martine Vrijheid; Anna Pierini; Rien J. M. Nijman; Marie-Claude Addor; Ingeborg Barisic; Judit Béres; Paula Braz; Judith Budd; Virginia Delaney; Miriam Gatt; Babak Khoshnood; Kari Klungsøyr; Carmen Martos; Carmel Mullaney; Vera Nelen; Amanda J. Neville; Mary O’Mahony; Annette Queisser-...; Hanitra Randrianaivo; Anke Rissmann; Catherine Rounding; David Tucker; Diana Wellesley; Natalya Zymak-Zak...; Marian K. Bakker; Hermien E. K. de ...
• Keywords: Nephrology; Patient registry

Hypospadias is a common congenital malformation. The prevalence of hypospadias has large geographical variation, and recent studies have reported both increasing decreasing temporal trends. It unclear whether associated with maternal age. To analyze the trends total hypospadias, isolated multiple anomalies, known cause, severity subtypes in Europe over 10-year period to investigate age hypospadias. We included all children born from 2001 2010 who were registered 23 EUROCAT registries. Information on number births distribution for registry population was also provided. analyzed relative risks by From 2010, 10,929 cases 5,871,855 births, yielding 18.61 per 10,000 births. Prevalence varied considerably between different registries, probably due differences ascertainment cases. No significant observed exceptions an trend anterior posterior unspecified After adjusting effects, not significantly Total stable registries influenced