Brain tumors in children under 1�year of age: emphasis on the relationship of prognostic factors

• DOI: 10.1007/s00381-003-0738-9
• Publication Date: 2003-11-24T16:57:49Z
• Authors: Roberto Rivera-Luna; Aurora Medina-Sanson; Carlos Leal-Leal; Francisco Pantoja...; Marta Zapata-Tarr�s; Rocio Cardenas-Ca...; Rafael Barrera-G�mez; Fernando Rueda-Fr...
• Keywords: Emphasis (telecommunications)

Primary brain tumors in infants under 12 months of age have a different prognosis from older children.A retrospective analysis was done in all patients less than 12 months old with primary brain tumors.Out of 1682 children with primary brain tumors, 61 (3.6%) were infants under 12 months old. The mean age at diagnosis was 181.6 days (SD 128) with a range of 1 to 364 days. There were 37 males (60.6%). The most common tumor was astrocytoma ( n=22) (36%). Supratentorial tumors were present in 63.9% but this was not related to survival ( p=0.1095). Complete surgical resection ( n=14) was favorable for survival ( p=0.039). Intracranial hypertension at diagnosis did not influence survival ( p=0.89). The overall survival rate was 32%, mean 42.08 (SD 7.38). A total of 24 patients are alive and without evidence of disease.Complete surgical resection was necessary for a favorable prognosis, and the long-term effects are a valid problem.