Bonus-freeze: benefit or risk? Two-year outcome and procedural comparison of a “bonus-freeze” and “no bonus-freeze” protocol using the second-generation cryoballoon for pulmonary vein isolation
Male
Time Factors
Time Factor
610 Medicine & health
Cryoballoon
Radiation Dosage
Radiography, Interventional
Pulmonary vein isolation
Cryosurgery
Risk Assessment
2705 Cardiology and Cardiovascular Medicine
Cardiac Catheters
Electrocardiography
03 medical and health sciences
0302 clinical medicine
Retrospective Studie
Risk Factors
Ambulatory
Atrial Fibrillation
Humans
Long-term follow-up
Aged
Retrospective Studies
Original Paper
Interventional
Cardiac Catheter
Risk Factor
Pulmonary Vein
General Medicine
Equipment Design
Middle Aged
Radiation Exposure
Atrial fibrillation
3. Good health
Radiography
Treatment Outcome
Pulmonary Veins
Fluoroscopy
10209 Clinic for Cardiology
Electrocardiography, Ambulatory
Female
Cardiology and Cardiovascular Medicine
Human
DOI:
10.1007/s00392-016-0987-8
Publication Date:
2016-04-16T08:22:01Z
AUTHORS (15)
ABSTRACT
Second-generation cryoballoon based pulmonary vein isolation has demonstrated encouraging acute and mid-term clinical outcome. Customarily, a bonus-freeze is applied after successful pulmonary vein isolation.To compare the long-term clinical outcome and safety profile of a bonus-freeze and a no bonus-freeze protocol.A total of 120 consecutive patients with paroxysmal [95/120 (79 %)] or persistent atrial fibrillation [25/120 (21 %)] underwent CB2-based PVI. Freeze-cycle duration was 240 s. In the first 60 patients a bonus-freeze was applied after successful PVI (group 1), while in the following 60 patients the bonus-freeze was omitted (group 2).Procedure and fluoroscopy times were significantly shorter in group 2 [113.8 ± 32 vs 138.2 ± 29 min (p = 0.03) and 19.2 ± 6 vs 24.3 ± 8 min (p = 0.02)]. No differences in procedural complications were found. During a mean follow-up of 849 ± 74 (group 1) and 848 ± 101 days (group 2, p = 0.13) 69 % of patients (group 1) and 67 % of patients (group 2) remained in stable sinus rhythm without any differences between the groups (p = 0.69).Freedom from atrial fibrillation after second-generation cryoballoon based pulmonary vein isolation and a follow-up of >2 years is comparable when applying a bonus- and a no bonus-freeze protocol, while procedure and fluoroscopy times are significantly shorter when omitting the bonus-freeze. No differences in periprocedural complications were identified.
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