Post-prandial muscle protein synthesis rates following the ingestion of pea-derived protein do not differ from ingesting an equivalent amount of milk-derived protein in healthy, young males

• DOI: 10.1007/s00394-023-03295-6
• Publication Date: 2024-01-16T18:01:56Z
• Authors: Philippe J. M. Pi...; Joey S. J. Smeets; Imre W. K. Kouw; Joy P. B. Goessens; Annemarie P. B. G...; Lisette C. P. G. ...; Lex. B. Verdijk; Luc J. C. van Loon; Tim Snijders
• Keywords: Plant protein; Muscle protein; Pea protein

Abstract Purpose Plant-derived proteins have received considerable attention as an alternative to animal-derived proteins. However, plant-derived are considered less anabolic properties when compared with The lower muscle protein synthesis rates following ingestion of plant- been attributed the essential amino acid content and/or their specific deficiencies. This study aimed compare post-prandial 30 g pea-derived milk-derived in healthy, young males. Methods In a randomized, double-blind, parallel-group design, 24 males (24 ± 3 y) primed continuous L-[ring- 13 C 6 ]-phenylalanine infusion after which they ingested pea (PEA) or (MILK). Blood and biopsies were collected frequently for 5 h assess plasma profiles subsequent rates. Results MILK increased concentrations more than PEA over period (incremental area under curve 151 31 vs 102 15 mmol∙300 min∙L −1 , respectively; P < 0.001). Ingestion both showed robust synthetic response no significant differences between treatments (0.053 0.013 0.053 0.017%∙h = 0.96). Conclusion Post-prandial do not differ from equivalent amount protein. International Clinical Trials Registry Platform (NTR6548; 27–06-2017).