Not simply a matter of psoriatic arthritis: epidemiology of rheumatic diseases in psoriatic patients

• DOI: 10.1007/s00403-012-1281-x
• Publication Date: 2012-08-06T02:52:52Z
• Authors: Gabriele De Marco; Angelo Cattaneo; Norma Battafarano; Ennio Lubrano; Carlo G. Carrera; Antonio Marchesoni
• Keywords: Adult; Aged, 80 and over; Male; Cooperative approach to psoriasis care; Epidemiology; Psoriasis; Psoriatic arthritis; Rheumatic diseases; Arthritis, Psoriatic; Comorbidity; Middle Aged; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Rheumatic Diseases; Prevalence; Humans; Psoriasis; Female; Aged; Follow-Up Studies; Retrospective Studies

This study investigated the occurrence of rheumatic conditions (RCs) in a psoriasis (PSO)-dedicated dermatological clinic. PSO subjects with musculo-skeletal discomfort, and/or carrying signs (articular/systemic, even asymptomatic) of RCs; and/or suffering flares of previously established psoriatic arthritis (PsA) were referred to rheumatologist for evaluation. Laboratory tests/imaging were performed as needed. Categorization adhered to RCs classification endorsed by the Italian Society of Rheumatology. Of the 1,200 psoriatic subjects, 277 (23.1 %) were enrolled (146 females). The mean age was 55.7 years (range 21-81), PSO duration was 13.5 years (range 0-62). Thirty-seven patients (13.4 %) were asymptomatic. On an average, 92 (7.6 %) patients/year were evaluated, of whom 79.4 % näive to rheumatological consultations (NRC). Osteoarthritis (OA) and PsA (isolated or combined) showed the highest prevalence, with 156 (56.3 %) and 110 cases (39.7 %), respectively. Among NRC subjects, the mean PsA annual incidence was 29.5 % (standard error of the mean ±5.4 %). Other RCs, isolated or associated with PsA/OA, were diagnosed in 31 cases (11.2 %). Thirty-two subjects (11.5 %) had arthralgias, 20 of whom due to congenital/mechanical disorders, the remaining were unclassifiable. In conclusion, the largest part (88.5 %) of PSO subjects referred to rheumatologist showed some RCs. On annual basis, 29.5 % of näive enrolled patients were diagnosed as PsA.