Clinical characteristics and treatment of Herlyn–Werner–Wunderlich syndrome

• DOI: 10.1007/s00404-014-3286-5
• Publication Date: 2014-05-27T05:27:38Z
• Authors: Jinhui Wang; Lan Zhu; Jinghe Lang; Zhufeng Liu; Dawei Sun; Jinhua Leng; Qingbo Fan
• Keywords: Adult; Menarche; China; Uterus; Syndrome; Kidney; 3. Good health; 03 medical and health sciences; Treatment Outcome; Vaginal Discharge; 0302 clinical medicine; Dysmenorrhea; Vagina; Humans; Abnormalities, Multiple; Female; Age of Onset; Retrospective Studies

To investigate the clinical characteristics and treatment of the Herlyn-Werner-Wunderlich syndrome (HWWS).Sixty-one patients diagnosed with HWWS were retrospectively analyzed. HWWS is categorized into three types in China.Age at presentation of all the cases was after menarche. The most common clinical presentations were dysmenorrhea for type I and vaginal discharge for types II and III. Clinical presentations of types II and III may not occur until reproductive age. HWWS occurred on the right in 39/61. Excision of the obstructed vaginal septum was the treatment utilized in this cohort. After surgery, subsequent pregnancies were ipsilateral in 52.9 %.Clinical presentation in untreated HWWS suggests the anatomic anomaly. Early recognition and treatment can reduce symptoms. Pregnancies occur in both the affected and unaffected uterus.