Clinical characteristics and perinatal outcome of fetuses with ventriculomegaly

• DOI: 10.1007/s00404-024-07599-8
• Publication Date: 2024-06-26T18:14:53Z
• Authors: Ebru Alici Davutoglu; Gorkem Arica; Nazli Ece Sahin; Ayse Kalyoncu Ucar; Ibrahim Adaletli; Zekeriyya Mehmet ...; Riza Madazli
• Keywords: Ventriculomegaly; Abnormality

Abstract Purpose To assess the incidence of associated structural anomalies, chromosomal/genetic abnormalities, infections, and perinatal outcomes fetuses with ventriculomegaly (VM), also to evaluate role fetal magnetic resonance imaging (MRI) in detecting intracranial anomalies. Methods Retrospective cohort study 149 prenatally diagnosed pregnancies VM. VM was classified as mild (Vp = 10–12 mm), moderate 12.1–15 severe > 15 mm). Fetal MRI performed 97 pregnancies. Results The incidences an CNS, non-CNS, chromosomal anomaly, genetic abnormality infection were 42.3%, 11.4%, 6.1%, 2.1% 1.3%, respectively. identified additional CNS anomalies 6.7% cases, particularly 18.8% termination pregnancy, 4% intrauterine 8.1% neonatal or infant death. rates alive at 12 months age neurological morbidity 2.6%, 11.1% 76.9% for mild, isolated VM, Conclusion prognosis mostly depends on severity Mild generally have favorable outcomes. is valuable