Value of endometrial biopsy in patients with hysteroscopically atrophic endometrium in patients with postmenopausal bleeding

• DOI: 10.1007/s00404-024-07922-3
• Publication Date: 2025-01-20T18:26:20Z
• Authors: Ayisha A. Ashmore; Abayomi I. Alao; Amie Hibbard; Libbi Burchnall; Natalie Menic; Summi Abdul; Viren Asher; Anish Bali; Shilpa Kolhe; Andrew Phillips
• Keywords: Endometrial biopsy

Abstract Purpose To determine the rate of precancer and cancer in women presenting with PMB who have a visually atrophic endometrium at hysteroscopy assess value endometrial biopsy this situation adequacy samples obtained. Methods Retrospective reviews all patients had presented an ET > / = 4 mm or < focal changes irregular features between 2013 2024 University Hospitals Derby Burton were included ( n 1096). Patients previously unclear findings excluded. The histology result was considered main outcome measure. Results 188 did not performed (17.15%), 660 benign pathology (60.22%), 239 inadequate sample (21.81%). Nine precancerous (0.82%). 0.00% 0). NPV cavity detecting 99.2%. pre-hysteroscopy 2.25 times more likely than those whose is to p 0.001, 95% CI 1.61–3.16). 10 initial repeat 23, 43.48%). Conclusions incidence precancer/cancer low. Many within cohort biopsy, therefore, sampling questionable value.