Autoimmune encephalitis: recent clinical and biological advances

• DOI: 10.1007/s00415-023-11685-3
• Publication Date: 2023-04-28T12:03:16Z
• Authors: James A. Varley; Christine Strippel; Adam Handel; Sarosh R. Irani
• Keywords: Autoimmune encephalitis; Neuroimmunology; Clinical Practice; Clinical phenotype

In 2015, we wrote a review in The Journal of Neurology summarizing the field autoantibody-associated neurological diseases. Now, 2023, present an update subject which reflects rapid expansion and refinement associated clinical phenotypes, further autoantibody discoveries, more detailed understanding immunological neurobiological pathophysiological pathways mediate these Increasing awareness around distinctive aspects their phenotypes has been key driver providing clinicians with better as to how diseases are best recognized. practice, this recognition supports administration often effective immunotherapies, making 'not miss' conditions. parallel, there is need accurately assess patient responses drugs, another area growing interest. Feeding into care basic biological underpinnings diseases, offer clear improved therapies toward enhanced outcomes. update, aim integrate diagnostic pathway advances management biology provide cohesive view on for patients future.