Robotic-assisted surgery for left-sided colon and rectal resections is associated with reduction in the postoperative surgical stress response and improved short-term outcomes: a cohort study

• DOI: 10.1007/s00464-024-10749-3
• Publication Date: 2024-03-18T16:01:42Z
• Authors: Abigail R. Ingham; Chia Yew Kong; Tin-Ning Wong; Stephen T. McSorley; Donald C. McMillan; Gary A. Nicholson; Ahmed Alani; David Mansouri; David Chong; Graham J. MacKay; Campbell S. D. Ro...
• Keywords: Surgical stress; Colorectal Surgery

Abstract Introduction There is growing evidence that the use of robotic-assisted surgery (RAS) in colorectal cancer resections associated with improved short-term outcomes when compared to laparoscopic (LS) or open (OS), possibly through a reduced systemic inflammatory response (SIR). Serum C-reactive protein (CRP) sensitive SIR biomarker and its utility early identification post-operative complications has been validated variety surgical procedures. remains paucity studies characterising RAS. Methods Retrospective study prospectively collected database consecutive patients undergoing OS, LS RAS for left-sided rectal single high-volume unit. Patient disease characteristics, CRP levels, clinical were reviewed, their relationships explored within binary logistic regression propensity scores matched models. Results A total 1031 included (483 376 LS, 172 RAS). lower levels across first 4 days ( p < 0.001) as well length stay OS unadjusted analyses. In models, was independently at Day 3 post-operatively (OR 0.35, 95% CI 0.21–0.59, reduction rate all 0.39, 0.26–0.56, major 0.5, 0.26–0.95, = 0.036). Within model comparing versus specifically, two days, proportion ≥ 150 mg/L (20.9% 30.5%, 0.036) (34.7% 46.7%, 0.033). Conclusions The present observational shows an approach postoperative SIR, better profile.