Percutaneous cementoplasty in multiple myeloma: a valuable adjunct for pain control and ambulation maintenance

• DOI: 10.1007/s00520-007-0344-6
• Publication Date: 2007-10-24T08:26:07Z
• Authors: Nhu Nam Tran Thang; German Abdo; Jean-Baptiste Martin; Yodit Seium-Neberay; Hasan Yilmaz; Marie-Christine V...; Daniel Rufenacht; Andre-Pascal Sappino; Pierre-Yves Dietrich
• Keywords: Adult; Male; Pain/etiology/prevention & control/surgery; Pain; Fractures, Bone; Young Adult; 03 medical and health sciences; 0302 clinical medicine; info:eu-repo/classification/ddc/616; Fractures Bone/complications/etiology/prevention & control/surgery; Humans; Spinal Fractures/complications/etiology/prevention & control/surgery; Aged; Pain Measurement; Retrospective Studies; ddc:616; Aged, 80 and over; Multiple Myeloma/complications/pathology; Vertebroplasty; Phlebography; Middle Aged; 3. Good health; Aged 80 and over; Spinal Fractures; Female; Vertebroplasty/instrumentation/methods; Multiple Myeloma

Bone pain and functional impairment are major concerns for multiple myeloma (MM) patients. The goal of this study was to better define the role of percutaneous cementoplasty (PC) in improving their quality of life.This retrospective analysis included 28 consecutive heavily pretreated MM patients managed at our institution between 1996 and 2002. They underwent a total of 34 PC procedures for the treatment of 117 vertebrae and 2 iliac sites and were evaluated at 1 month.Significant pain reduction of >50% was obtained after 83% of the procedures, with a mean visual analogous score decreasing from 7.48/10 to 2.1/10 (p < 0.001). It resulted in a complete interruption of opiate analgesic consumption after 59.3% of the procedures, with a mean decrease of 70.4% in the opiate dose. Functional impairment was evaluated with the Eastern Cooperative Oncology Group (ECOG) performance status scale, with mean scores improving from 1.9 to 0.86 after the procedures (p = 0.001). There was no major complication.PC is a safe, feasible, and efficient approach for the treatment of bone pain and disability in MM patients.