Sensitive fluorescent light-up probe for enzymatic determination of glucose using carbon dots modified with MnO2 nanosheets

• DOI: 10.1007/s00604-016-2004-3
• Publication Date: 2016-11-08T11:21:41Z
• Authors: Hong Ma; Xiaoyu Liu; Xudong Wang; Xinran Li; Chengduan Yang; Anam Iqbal; Weisheng Liu; Jiping Li; Wenwu Qin
• Keywords: 01 natural sciences; 0104 chemical sciences

We describe a highly sensitive glucose probe based on carbon dots modified with MnO2. A strong reduction of the green fluorescence of the carbon dots (CDs) happened due to the surface energy transfer (SET) from CDs to the deposited MnO2. In the presence of H2O2 (formed via enzymatic oxidation of glucose), fluorescence is restored because the MnO2 nanosheets are reduced to form colorless Mn(II) ions. These findings were used to design a fluorometric glucose assay that has a detection limit as low as 44 nM (at an S/N ratio of 3).