Proposal for a fourth aquabirnavirus serogroup

• DOI: 10.1007/s00705-008-0192-9
• Publication Date: 2008-09-16T07:29:45Z
• Authors: P. F. Dixon; G.-H. Ngoh; D. M. Stone; S. F. Chang; K. Way; S. L. F. Kueh
• Keywords: 0301 basic medicine; Genotype; Sequence Homology, Amino Acid; Molecular Sequence Data; Fishes; Sequence Analysis, DNA; Antibodies, Viral; RNA-Dependent RNA Polymerase; Aquabirnavirus; Viral Proteins; 03 medical and health sciences; Neutralization Tests; Animals; RNA, Viral; 14. Life underwater; Serotyping; Phylogeny

Four putative aquabirnaviruses, based on morphology, nucleic acid type and partial RNA-dependent RNA polymerase gene (VP1) sequence, isolated from three tropical freshwater fish species were not neutralised by antisera against type members of the Aquabirnavirus genus serogroups A, B or C. Antisera produced against two of the isolates neutralised the homologous and heterologous isolates, but not any type member of Aquabirnavirus serogroups A, B or C. The serological comparisons suggest that the four isolates should be regarded as members of a fourth Aquabirnavirus serogroup, D.