The association of unplanned pregnancy with perinatal depression: a longitudinal cohort study

• DOI: 10.1007/s00737-022-01225-9
• Publication Date: 2022-03-29T01:03:41Z
• Authors: Lotte Muskens; Myrthe G. B. M. B...; Willem J. Kop; Marion I. van den...; Victor J. M. Pop; Annemerle Beerthu...
• Keywords: SYMPTOMS; UNINTENDED PREGNANCY; Perinatal; SECONDARY DATA-ANALYSIS; Cohort Studies; Depression, Postpartum; Unplanned pregnancy; 03 medical and health sciences; 0302 clinical medicine; SDG 3 - Good Health and Well-being; Pregnancy; Risk Factors; ANXIETY; Humans; Edinburgh Postnatal Depression Scale; POSTNATAL DEPRESSION; 0501 psychology and cognitive sciences; Longitudinal Studies; Mixed models; Psychiatric Status Rating Scales; Depression; 05 social sciences; POSTPARTUM DEPRESSION; Pregnancy, Unplanned; PREVALENCE; 3. Good health; Cross-Sectional Studies; Longitudinal; RISK-FACTORS; Original Article; Female; TRAJECTORIES; MENTAL-HEALTH

Abstract Perinatal depression is common, affecting approximately 7–13% of women. Studies have shown an association between unplanned pregnancy and perinatal depressive symptoms, but many used a cross-sectional design and limited postnatal follow-up. The current study investigated the association of unplanned pregnancy with perinatal depressive symptoms using a longitudinal cohort study that followed women from the first trimester until 12 months postpartum. Pregnant women (N = 1928) provided demographic and clinical data and information about pregnancy intention at the first trimester. Depressive symptoms were assessed during each trimester of pregnancy and five times postpartum using the Edinburgh Postnatal Depression Scale (EPDS) until 12 months postpartum. Mixed model analyses were used to investigate the association between an unplanned pregnancy and the level of depressive symptoms. Women with an unplanned pregnancy (N = 111, 5.8%) reported persistently higher levels of depressive symptoms during the entire perinatal period compared to women with a planned pregnancy, after adjustment for confounders (p < 0.001). However, the course of depressive symptom scores over time in women with an unplanned pregnancy was similar to that of women with a planned pregnancy. Lower age (p = 0.006), unemployment (p = 0.004), and history of depression (p < 0.001) were significantly associated with higher levels of perinatal depressive symptoms. An unplanned pregnancy may have a long-lasting negative impact on a woman’s perinatal mental health. Therefore, women with an unplanned pregnancy may benefit from systematic follow-up during the perinatal period with contingent mental health support.