Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults

• DOI: 10.1007/s00784-014-1221-6
• Publication Date: 2014-03-18T03:29:22Z
• Authors: Aino Toiviainen; Heli Jalasvuori; Emilia Lahti; Ulvi Gursoy; Seppo Salminen; Margherita Fontana; Susan Flannagan; George Eckert; Alexis Kokaras; Bruce Paster; Eva Söderling
• Keywords: Bifidobacterium animalis; Lozenge; Lactobacillus rhamnosus; Gingival inflammation; Dysbiosis; Dental plaque

The aim was to evaluate the effects of orally administered Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on number salivary mutans streptococci (MS), amount plaque, gingival inflammation oral microbiota in healthy young adults. study a randomised, controlled, double-blind trial. Healthy volunteers used lozenges containing combination LGG (test group, n = 29) or without added probiotics (control 31) for 4 weeks. At baseline at end test period, plaque index (PI) (GI) were determined, stimulated saliva collected. microbial composition assessed using human microbe identification microarray (n 30). MS lactobacilli (LB) plate cultured. probiotic lozenge decreased both PI GI (p < 0.05) while no changes observed control group. However, probiotic-induced found compositions either improved periodontal status affecting microbiota. Short-term consumption which associated with clinical impact: decrease inflammation.