The use of Schirmer strips to measure salivary and lacrimal flow in non-Sjögren patients

• DOI: 10.1007/s00784-020-03741-3
• Publication Date: 2021-01-03T13:02:47Z
• Authors: Dominika Wróbel-D...; Agnieszka Kubik-K...; Dorota Rykwa; Ewa Kosior-Jarecka; Tomasz Żarnowski; Renata Chałas
• Keywords: 03 medical and health sciences; Sjogren's Syndrome; 0302 clinical medicine; Lacrimal Apparatus; Humans; Original Article; Dry Eye Syndromes; Xerostomia; Salivary Glands; 3. Good health

Abstract Introduction Oral and ocular dryness are the most common symptoms reported during ophthalmological and dental examinations. It is becoming a serious and growing problem due to the huge variety of affecting factors and with population aging.

Objectives The purpose was to demonstrate an application of the Schirmer test for xerostomia. Subsequently, to compare and correlate the results achieved from the lacrimal Schirmer test and salivary Schirmer test in non-Sjögren patients.

Methods Study group consisted of 642 patients with/without subjective or/and objective symptoms of dry eye or mouth who did not fulfill the criteria for diagnosis of Sjögren syndrome. The lacrimal Schirmer test (lST) and the salivary Schirmer tests (sST) were performed (sSTm was put on the floor of the mouth, sSTp in front of the parotid gland duct). The results were recorded after 1 min (sSTm), 3 min (sSTp), and 5 min (lST).

Results The lST and sST test scores were considerably higher in the healthy group than in others, p < 0.001. The results of sST1 and sST2 decreased with the appearance of subjective and objective symptoms, p < 0.001. There were positive correlations between lST and sSTm outcomes between the groups, p < 0.001.

Conclusions We present the Schirmer test adapted to measure salivary gland hypofunction that is a time-saving tool in our daily practice. Results of this study reveal an excellent correlation between the eye Schirmer test and the salivary Schirmer tests.

Clinical relevance The salivary Schirmer tests seem to be rapid, convenient, and reliable objective screening tools for salivary gland hypofunction in non-Sjögren patients.