Treatment of multiple adjacent gingival recessions using leucocyte- and platelet-rich fibrin with coronally advanced flap: a 12-month split-mouth controlled randomized clinical trial

• DOI: 10.1007/s00784-024-05694-3
• Publication Date: 2024-05-01T12:52:52Z
• Authors: Atacan Yavuz; Hatice Selin Güng...; Leyla Kuru; Başak Doğan
• Keywords: Platelet-rich fibrin; Gingival recession; Gingival margin

Abstract Objective This split-mouth randomized study aimed to assess efficacy of leucocyte-platelet-rich fibrin (L-PRF) versus connective tissue graft (CTG) in achieving root coverage (RC) for multiple adjacent gingival recessions (MAGRs) throughout 12-month period. Materials and methods The enrolled 59 teeth from 12 patients with Miller Class I MAGRs ≥ 2 mm on bilateral or contralateral sides. Patients were randomly assigned receive coronally advanced flap (CAF) either CTG (control) L-PRF (test) treatment. Various parameters, including plaque index, clinical attachment level, recession depth, probing width (RW), papilla (PW), keratinized (KTW), thickness (GT), percentage RC, complete (CRC), location the relative margin concerning cemento-enamel junctions (GMCEJ) after CAF, recorded at baseline, 3-, 6-, 12-months post-surgery. On June 29, 2021 was registred ClinicalTrials.gov (NCT04942821). Results Except KTW GT gain, all CRC similar between groups follow-up periods ( p > 0.05). higher gains detected control group compared test months < Both RC positively associated initial PW GMCEJ, but negatively RW Conclusions current concludes that equally effective as treating terms CRC. Additionally, outcomes appeared be influenced by PW, RW. Clinical relevance could represent a feasible substitute MAGRs.