Altered functional connectivity of the hippocampus with the sensorimotor cortex induced by long-term experience of virtual hand illusion

• DOI: 10.1007/s10055-023-00838-4
• Publication Date: 2023-08-02T05:01:46Z
• Authors: Shanshan Chen; Gang Hu; Xiangfeng Meng; Jie Guo; Hui Fang; Haiyan Jiang; Dongdong Weng
• Keywords: 0301 basic medicine; 03 medical and health sciences

Abstract Synchronizing the movement of a virtual hand with an unseen real in environment is effective method to induce sense ownership hand. Although several neuroimaging studies have revealed neural mechanisms related ongoing process illusion, effect long-term experience illusion on brain activity remains be investigated. Here, we developed apparatus based real-time image matting and reality technology which allowed us use participants’ hands as their synchronize scene. Resting-state functional imaging data were acquired immediately after participants completed light office tasks either (virtual condition) or (real condition). Significant positive connectivity hippocampus primary somatosensory motor cortex was only observed condition. The results provided novel evidence for involvement hippocampal-sensorimotor connection ownership. reorganization might promote multi-sensory information integration into memory updated body ownership, offered important insights network underlying availability VR healthcare rehabilitation.