Streptococcus salivarius by nasal spray for recurrent otitis: how good is the evidence?

• DOI: 10.1007/s10096-016-2648-2
• Publication Date: 2016-05-14T12:50:42Z
• Authors: S. Di Mario; V. Basevi; R. D’Amico; C. Gagliotti; M. Gangemi; F. Marchetti; M. L. Moro; G. Tamburlini
• Keywords: Microbiology (medical); Infectious Diseases; 03 medical and health sciences; Treatment Outcome; 0302 clinical medicine; Recurrence; Humans; Otitis; Nasal Sprays; Streptococcus salivarius; Anti-Bacterial Agents

This is a letter published after a paper by Marchisio et al. entitled ‘Streptococcus salivarius 24SMB administered by nasal spray for the prevention of acute otitis media (AOM) in otitis-prone children’ was published. The paper raised some methodological concerns that were expressed in the letter.