Risk factors for enterococcal urinary tract infections: a multinational, retrospective cohort study

• DOI: 10.1007/s10096-021-04207-4
• Publication Date: 2021-03-02T08:02:49Z
• Authors: Adi Turjeman; Tanya Babich; Miquel Pujol; Jordi Carratalà; Evelyn Shaw; Aina Gomila-Grange; Cuong Vuong; Ibironke Addy; Irith Wiegand; Sally Grier; Alasdair MacGowan; Christiane Vank; Nienke Cuperus; Leo van den Heuvel; Leonard Leibovici; Noa Eliakim-Raz
• Keywords: Antibiotic stewardship; Male; 0301 basic medicine; Internationality; Complicated urinary tract infection (UTI); Middle Aged; Anti-Bacterial Agents; 3. Good health; Europe; Hospitalization; Middle East; 03 medical and health sciences; Risk factors; Risk Factors; Urinary Tract Infections; Humans; Female; Enterococcus; Aged; Retrospective Studies

Complicated urinary tract infection (cUTI) is a frequent cause of morbidity. In this multinational retrospective cohort study, we aimed to demonstrate risk factors for enterococcal UTI. Univariate and multivariate analyses of risk factors for enterococcal infection were performed. Among 791 hospitalized patients with cUTI, enterococci accounted for approximately 10% of cases (78/791). Risk factors for enterococcal UTI in multivariable analysis were male gender, age range of 55-75 years, catheter-associated UTI, and urinary retention. This information may assist treating physicians in their decision-making on prescribing empiric anti-enterococcus treatment to hospitalized patients presenting with cUTI and thus improve clinical outcomes.