Effect of the intravascular low energy laser illumination during percutaneous coronary intervention on the inflammatory process in vascular wall

• DOI: 10.1007/s10103-012-1142-z
• Publication Date: 2012-06-27T05:35:24Z
• Authors: Arkadiusz Derkacz; Marcin Protasiewicz; Rafał Poręba; Adrian Doroszko; Ryszard Andrzejak
• Keywords: Intravascular Ultrasound

The angioplasty procedure is associated with a release of numerous factors triggering the local inflammatory reaction in vascular wall and leading thus to restenosis. In this study, we hypothesize that low-energy laser irradiation may exert beneficial effect by limiting process. A group 101 subjects (75 men 26 women, mean age: 59.1 ± 10.3) treated percutaneous coronary intervention (PCI), were recruited study. While 52 patients (40 12 women) subjected intravascular (λ = 808 nm) dilated lesion during PCI, remaining (35 14 constituted control group. levels interleukin 1β, 6 10 (IL IL 10) measured immediately before procedure, then at 6th, 12th hour as well after 1 month following PCI. Significantly lower 1β irradiated each analysis observed. Moreover, significantly level within hours PCI was Irradiation radiation results decrease pro-inflammatory an increase anti-inflammatory 10, which result decreased risk for