Factors influencing health-related quality of life after gastrectomy for cancer

• DOI: 10.1007/s10120-017-0771-0
• Publication Date: 2017-10-24T08:44:37Z
• Authors: Hylke J. F. Brenkman; Juul J. W. Tegels; Jelle P. Ruurda; Misha D. P. Luyer; Ewout A. Kouwenhoven; Werner A. Draaisma; Donald L. van der...; Bas P. L. Wijnhoven; Jan H. M. B. Stoot; Richard van Hille...
• Keywords: Surgical oncology; Cancer surgery

Insight in health-related quality of life (HRQoL) may improve clinical decision making and inform patients about the long-term effects gastrectomy. This study aimed to evaluate identify factors associated with HRQoL after cross-sectional used prospective databases from seven Dutch centers (2001–2015) including who underwent gastrectomy for cancer. Between July 2015 November 2016, European Organization Research Treatment Cancer questionnaires QLQ-C30 QLQ-STO22 were sent all surviving without recurrence. The scores compared a reference population using one-sample t test. Spearman's rank test was correlate time surgery HRQoL, multivariable linear regression performed HRQoL. A total 222 274 (81.0%) completed questionnaires. Median follow-up 29 months (range, 3–171) 86.9% had >1 year. majority undergone neoadjuvant treatment (64.4%) (52.7%). Minimally invasive (MIG) 50% patients. Compared general population, scored significantly worse on most functional symptom scales (p < 0.001) slightly global (78 vs. 74, p = 0.012). Time elapsed since did not (Spearman's ρ 0.06, 0.384). Distal gastrectomy, treatment, MIG better 0.050). After encounter impairments symptoms, but experience only impaired ability receive be benefits.