Psychosocial Factors Linked to Uncontrolled Infection and Mortality among People Living with HIV Who Use Substances: A Latent Class Analysis

• DOI: 10.1007/s10461-024-04410-2
• Publication Date: 2024-08-02T13:12:43Z
• Authors: Renae D. Schmidt; Viviana E. Horigian; Rui Duan; Sharleen T. Traynor; Carly A. Davis; Sophia T. Gonzalez; Derrick J. Forney; Raul Mandler; Carlos Del Rio; Lisa R. Metsch; Daniel J. Feaster
• Keywords: Health psychology

Abstract To determine whether endorsement patterns of psychosocial symptoms revealed distinct subgroups, or latent classes, people living with HIV who use substances (PLWH-SU), and to assess these classes demonstrated differential health outcomes over time. This study uses data from 801 PLWH-SU initially enrolled across 11 US hospitals during 2012–2014 followed up in 2017. Latent class analysis included 28 items. Regression examined membership as a predictor viral suppression. Survival all-cause mortality. The selected model identified five unique classes. Individuals characterized by more severe numerous at baseline had lower likelihoods suppression survival. the importance considering overlapping identify subgroups reveal their risks for adverse outcomes. Integration primary, mental health, substance care is essential address needs this population.