Effects of silymarin (hepatoprotector) and succinic acid (bioenergy regulator) on metabolic disorders in experimental diabetes mellitus

• DOI: 10.1007/s10517-007-0252-2
• Publication Date: 2007-11-12T11:54:06Z
• Authors: A. I. Vengerovskii; V. A. Khazanov; K. A. Eskina; K. Yu. Vasilyev
• Keywords: Succinic acid

Silymarin (70 mg/kg) and succinic acid (50 mg/kg) reduce blood glucose and cholesterol concentrations, inhibit LPO, and correct oxidative phosphorylation disturbances in liver mitochondria in experimental diabetes mellitus induced by injection of streptozotocin (65 mg/kg) in rats.