Serotonin Metabolism Parameters in Patients with Chronic Hepatitis and Liver Cirrhosis

• DOI: 10.1007/s10517-009-0353-1
• Publication Date: 2009-03-13T05:17:35Z
• Authors: A. S. Alekseeva; E. I. Beloborodova; M. I. Rachkovskiy; E. L. Naumova; E. G. Lambrov; L. P. Philippova
• Keywords: Adult; Liver Cirrhosis; Male; 0301 basic medicine; Depressive Disorder; Serotonin; Middle Aged; 3. Good health; Young Adult; 03 medical and health sciences; Humans; Female; Hepatitis, Chronic

We studied disorders in serotonin metabolism in patients with chronic hepatitis and cirrhosis of the liver with and without inflammatory process (cytolysis syndrome) and their impact for the formation of depressive disorders. Blood serotonin content decreased in patients with cirrhosis of the liver with pronounced depressive disorders. Serum serotonin level was elevated in all patients with the cytolysis syndrome.