Nitrogen Metabolism in Rats with Experimental Diabetes during Acute Alcohol Intoxication

• DOI: 10.1007/s10517-011-1446-1
• Publication Date: 2011-11-16T22:06:45Z
• Authors: N. V. Zharkova; P. P. Potapov; A. Yu. Stelmach
• Keywords: Male; Ethanol; Central Nervous System Depressants; Blood Urea Nitrogen; Diabetes Mellitus, Experimental; Rats; Uric Acid; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Glutamate Dehydrogenase; Liver; Aminohydrolases; Alloxan; Animals; Amino Acids; Alcoholic Intoxication; Transaminases

The concentrations of urea and uric acid increased, while the content of free amino acids decreased in blood serum from rats with alloxan-induced diabetes during acute alcohol intoxication. Activities of glutamate dehydrogenase, AMP deaminase, and tyrosine aminotransferase in the liver of experimental animals increased.