Relaxation Properties of Contrast Media for MRI Based on Iron Oxide Nanoparticles in Different Magnetic Fields

• DOI: 10.1007/s10517-019-04469-1
• Publication Date: 2019-06-10T04:02:38Z
• Authors: V. P. Chekhonin; M. A. Abakumov; A. G. Mazhuga; A. N. Bagdinova; E. I. Demikhov; T. E. Demikhov; B. Ya. Mishkinis; M. V. Konstantinov; V. P. Tarasov; B. A. Shumm; A. A. Gippius; N. V. Gervits; A. B. Shumm
• Keywords: Iron oxide nanoparticles

We studied dependences of T2 relaxation time on magnetic field and concentration of nanoparticles. It was found that nanocontrast media are effective under the influence of the magnetic fields in the range 0.3-7 T. Data of electron paramagnetic resonance confirm the assumption on aggregation of nanoparticles not coated with proteins in high magnetic fields.