Cardiac imaging phenotype in patients with coronavirus disease 2019 (COVID-19): results of the cocarde study

• DOI: 10.1007/s10554-020-02010-4
• Publication Date: 2020-09-10T11:22:41Z
• Authors: Olivier Lairez; Virginie Blanchard; Valérie Houard; Fanny Vardon-Bounes; Maeva Lemasle; Eve Cariou; Yoan Lavie-Badie; Stéphanie Ruiz; Stéphanie Cazalbou; Clément Delmas; Bernard Georges; Michel Galinier; Didier Carrié; Jean-Marie Conil; Vincent Minville
• Keywords: Pathophysiology

Biological cardiac injury related to the Severe Acute Respiratory Syndrome Coronavirus-2 infection has been associated with excess mortality. However, its functional impact remains unknown. The aim of our study was explore biological on myocardial functions in patients COVID-19. 31 confirmed COVID-19 (CoV+) and 16 controls (CoV-) were prospectively included this observational study. Demographic data, laboratory findings, comorbidities, treatments function assessed by transthoracic echocardiography collected analysed CoV+ (TnT+) without (TnT-) elevation troponin T levels compared CoV-. Among CoV+, 13 (42%) exhibited injury. CoV+/TnT + older, had lower diastolic arterial pressure more likely have hypertension chronic renal failure CoV+/TnT-. control group comparable except for an absence inflammatory syndrome. Left ventricular ejection fraction global longitudinal strain not different among three groups. There a trend decreased work increased peak systolic tricuspid annular velocity between CoV- CoV patients, which became significant when comparing CoV+/TnT+ (2167 ± 359 vs. 1774 521%/mmHg, P = 0.047 14 3 cm/s, 0.037, respectively). decrease efficiency from (96 2%) CoV+/TnT- (94 4%) then (93 3%, 0.042). In conclusion, COVID 19 low left function.