Impairment of right ventricular longitudinal strain associated with severity of pneumonia in patients recovered from COVID-19

• DOI: 10.1007/s10554-021-02214-2
• Publication Date: 2021-04-11T07:02:44Z
• Authors: Pelin Karaca Ozer; Elif Ayduk Govdeli; Derya Baykiz; Ekrem Bilal Karaa...; Alpay Medetalibey...; Yunus Catma; Ali Elitok; Atahan Cagatay; Berrin Umman; Aytac Oncul; Tufan Tukek; Zehra Bugra
• Keywords: Male; Original Paper; Heart Ventricles; Ventricular Dysfunction, Right; Age Factors; COVID-19; Middle Aged; Severity of Illness Index; 3. Good health; 03 medical and health sciences; Sex Factors; 0302 clinical medicine; Echocardiography; Case-Control Studies; Humans; Female; Prospective Studies; Glucocorticoids

Myocardial injury caused by COVID-19 was reported in hospitalized patients previously. But the information about cardiac consequences of after recovery is limited. The aim study comprehensive echocardiography assessment right ventricular (RV) recovered from COVID-19. This a prospective, single-center study. After COVID-19, performed consecutive 79 that attended follow-up visits July 15 to November 30, 2020. According at home vs hospital, were divided into two groups: (n = 43) and hospital 36). Comparisons made with age, sex risk factor-matched control group 41). In addition conventional parameters, RV global longitudinal strain (RV-GLS) free wall (RV-FWS) determined using 2D speckle-tracking (2D STE). Of 43 (55%) home, while 36 (45%) required hospitalization. median duration 133 ± 35 (87-184) days. RV-GLS RV-FWS impaired compared (RV-GLS: -17.3 6.8 vs. -20.4 4.9, respectively [p 0.042]; RV-FWS: -19.0 8.2 -23.4 6.2, 0.022]). subgroup analysis, severe pneumonia 11) mild-moderate 28), without 40) groups (-15.8 7.6 -21.6 -20.8 7.7 respectively, 0.001 for each]) (-15.2 6.9 4; 0.013]). A significant correlation detected between serum CRP level admission both (r 0.285, p 0.006; r 0.294, 0.004, respectively). Age (OR 0.948, 0.010), male gender 0.289, 0.009), on CT 0.019, 0.004), need steroid treatment 17.424, 0.038) identifed as independent predictors (> -18) via multivariate analysis. We demonstrated subclinic dysfunction 2D-STE relation severity supplies additional above standard measures this cohort can be used these patients.