Sleep-Wake Patterns of Adolescents with Borderline Personality Disorder and Bipolar Disorder

• DOI: 10.1007/s10578-015-0557-8
• Publication Date: 2015-05-23T06:49:04Z
• Authors: Christophe Huỳnh; Jean-Marc Guilé; Jean-Jacques Breton; Roger Godbout
• Keywords: Male; Sleep Wake Disorders; Bipolar Disorder; Adolescent; Comorbidity; Circadian Rhythm; 3. Good health; [SDV] Life Sciences [q-bio]; 03 medical and health sciences; 0302 clinical medicine; Borderline Personality Disorder; Humans; Female; Wakefulness; Sleep

Sleep-wake patterns are rarely examined in adolescents with borderline personality disorder (BPD) or bipolar disorder (BD). Within a developmental perspective, this study explores the sleep-wake cycle of adolescents aged 12-17 years with BPD or BD and healthy controls (HC) during periods with and without entrainment by school/work schedules. Eighteen euthymic BPD, six euthymic BD, and 20 HC adolescents wore wrist actigraphy during nine consecutive days to assess sleep-wake patterns. During school/work days, BPD adolescents spent more time awake when they were in bed compared to HC and BD adolescents (p = 0.039). On schedule-free days, BPD and BD youths spent more time in bed compared to HC adolescents (p = 0.015). BPD adolescents woke up over 1 h later compared to HC (p = 0.003). Total sleep time was more variable between nights in BPD adolescents compared to the HC group (p = 0.031). Future research should explore if sleep-wake pattern disruptions are a cause or a consequence of BPD symptomatology in adolescents. Addressing sleep-wake pattern during clinical assessment and treatment of BPD adolescents may potentially reduce their symptoms; this therapeutic effect still needs to be evaluated.