New macrocycles with potent antituberculosis activity accessed by one-pot multicomponent reactions

• DOI: 10.1007/s10593-013-1319-9
• Publication Date: 2013-09-04T04:55:19Z
• Authors: D. Kim; Y. Huang; K. Wang; A. Dömling
• Keywords: Tylosin

AbstractTylosin derivatives (III) and (VII) are synthesized by Gewald or Ugi three‐component reaction, resp., and evaluated for their antituberculosis activities.