Synthesis of Novel 2-Hetarylpyrrolidines via the Reaction of N-(4,4-diethoxybutyl)amidophosphates with C-nucleophiles

• DOI: 10.1007/s10593-020-02823-0
• Publication Date: 2020-11-16T07:03:35Z
• Authors: Andrey V. Smolobo...; Rakhymzhan A. Tur...; Almir S. Gazizov; Elizaveta A. Kuzn...; Alexander R. Burilov; Mikhail A. Pudovik
• Keywords: Trifluoroacetic acid; Reaction conditions

The reactions of N-(4,4-diethoxybutyl)amidophosphates with С-nucleophiles in chloroform in the presence of trifluoroacetic acid provided new 2-hetarylpyrrolidines. The reaction proceeded under mild conditions and gave good yields in the absence of metal-based catalysts.