Cryoballoon ablation of atrial fibrillation in octogenarians: one year outcomes from the cryo global registry
Registry
Octogenarians
610
Catheter ablation
Cryoballoon
Atrial fibrillation
Article
DOI:
10.1007/s10840-023-01680-z
Publication Date:
2023-12-12T03:02:16Z
AUTHORS (11)
ABSTRACT
Abstract Background Limited information is available on the safety and efficacy of cryoballoon ablation (CBA) in elderly patients with atrial fibrillation (AF). Moreover, global utilization CBA this population (≥ 80 years old) has not been reported. This study’s objectives were to determine use, efficacy, treat octogenarians suffering from AF. Methods In sub-analysis Cryo Global Registry, 12-month outcomes treating AF via compared < old. Efficacy was evaluated as time a ≥ 30 s arrhythmia (AA) recurrence. Healthcare determined repeat ablations hospitalizations. Improvement upon disease burden through patient reporting symptoms EQ-5D-3L quality life (QoL) survey. Results The octogenarian cohort (n = 101) had higher prevalence females (51.5% vs 35.7%) CHA 2 DS -VASc scores (4.2 ± 1.3 2.0 1.5) control 1573, both p 0.01). Even when adjusting for baseline characteristics antiarrhythmic drug usage, freedom AA recurrence at 12 months (80.6% 78.9%, HR adj :0.97 [95% CI:0.59–1.58], 0.90) comparable between control, respectively. Similar serious adverse event rates observed (5.0%) (3.2%, 0.38). groups did differ healthcare nor reduction AF-related follow-up, but experienced an improvement QoL months. Conclusions Despite more age-related comorbidities, safe effective treatment octogenarians, events akin performed younger patients. Clinical trial registration https://clinicaltrials.gov/ct2/show/NCT02752737 Graphical
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