Thirteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer

• DOI: 10.1007/s10911-022-09526-6
• Publication Date: 2022-10-15T08:03:01Z
• Authors: Alecia-Jane Twigger; Jakub Sumbal; Mohamed Bentires-Alj; Beatrice A Howard
• Keywords: Patient-derived Xenografts; 570; 610; Lobular breast cancer; Breast Neoplasms; Meeting Report; Lobular Breast Cancer; Mice; 03 medical and health sciences; Mammary Glands, Animal; Breast cancer; ductal carcinoma in situ; Breast Development; Resistance To Endocrine Therapy; 616; Animals; Humans; Lactation; In Vivo Live Imaging; Mammary Glands, Human; Pandemics; Biology; Mammary Gland Biology; 0303 health sciences; Ductal carcinoma in situ; COVID-19; Breast development; 3. Good health; Organoids; In vivo live imaging; Patient-derived xenografts; Resistance to endocrine therapy; Mammary gland biology; Female

AbstractThe thirteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) Laboratories Annual Workshop took place on the 28–30 April 2022 in Weggis, Switzerland and focused on methods in mammary gland biology and breast cancer. Sixty scientists participated in the ENBDC annual workshop which had not been held in person since 2019 due to the global COVID-19 pandemic. Topics spanned the mammary gland biology field, ranging from lactation biology and embryonic development, single cell sequencing of the human breast, and stunning cutting-edge imaging of the mouse mammary gland and human breast as well as breast cancer research topics including invasive progression of the pre-invasive DCIS stage, metabolic determinants of endocrine therapy resistance, models for lobular breast cancer, and how mutational landscapes of normal breast during age and pregnancy determine cancer risk. The latest findings from participating researchers were presented through oral presentations and poster sessions and included plenty of unpublished work.