Psoas Abscesses Caused by Paracoccidioides brasiliensis in an Adolescent

Male 0301 basic medicine 0303 health sciences Antifungal Agents Adolescent Fever Paracoccidioides Directly Observed Therapy 3. Good health Radiography 03 medical and health sciences Amphotericin B Trimethoprim, Sulfamethoxazole Drug Combination Humans Patient Compliance Psoas Abscess Lymph Nodes Itraconazole Paracoccidioidomycosis Child Infusions, Intravenous
DOI: 10.1007/s11046-008-9152-x Publication Date: 2008-09-09T09:42:07Z
ABSTRACT
In order to describe the case of an adolescent who developed psoas abscesses caused by Paracoccidiodes brasiliensis.A 12-year-old boy was admitted with a history of daily fever and global lymph nodes enlargement. He had been treated in the last 6 years, with irregular use of the drugs, for an acute form of paracoccidioidomycosis (PCM). He presented a tenderness fluctuating polyadenopathy in all cervical, submandibular, supraclavicular, axillary, and inguinal chains; several lymph nodes were up to 4 cm in diameter, hardened and coalescent. After 1 month of unsuccessful therapy with SMX-TMP, the patient presented a pain in the right groin and difficulty to walk. CT scan showed a global retroperitoneal lymph nodes enlargement, some with central necrosis and two bigger collections adjacent to both psoas muscles. A surgical drainage of the collections was performed for several times. The patient received a total of 1.9 g of Amphotericin B. After 1 month of the last surgical procedure, CT scan showed only a residual collection, and the patient was sent to ambulatory follow-up. We hypothesed that the retroperitoneal lymph nodes became a coalescent mass that fistulized to the psoas compartment.The patient presented a febrile lymphoproliferative syndrome that is frequently seen in children with PCM. Although a polymorphic manifestation is observed in this disease, psoas abscess is a rare complication of PCM. The health professionals that take care of the patients with PCM must pay attention to the possibility of this one more complication.
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