Evaluation of a multifaceted medication review in older patients in the outpatient setting: a before-and-after study

• DOI: 10.1007/s11096-022-01531-3
• Publication Date: 2023-02-06T12:03:09Z
• Authors: N.A. Zwietering; A. E. M. J. H. Li...; P. H. M. van der Kuy; H. Cremers; N. van Nie-Visser; K. P. G. M. Hurkens; Bart Spaetgens
• Keywords: Frail Elderly; Medication Review; Pharmacists; Hospitals; 3. Good health; Hospitalization; 03 medical and health sciences; Drug Utilization Review; 0302 clinical medicine; Outpatients; 80 and over; Polypharmacy; Humans; Aged-Aged; Emergency Service, Hospital; Research Article; Aged

Abstract Background The prevalence of medication-related emergency department visits and acute hospital admissions in older patients is rising due to the ageing of the population and increasing prevalence of multimorbidity and associated polypharmacy.

Aim To explore whether a combined medication review performed in the outpatient setting reduces the number of medication-related emergency department visits and hospital (re)admissions.

Method All consecutive patients visiting the geriatric outpatient clinic underwent a multifaceted medication review (i.e. evaluation by at least a geriatrician, and/or pharmacist and use of clinical decision support system). Subsequently, we analysed the number of, and reason for, emergency department visits, acute hospital admissions and readmissions in the year prior to and the year following the index-date (date of first presentation and medication review).

Results A multifaceted medication review reduced the number of potentially medication-related emergency department visits (38.9% vs. 19.6%, p < 0.01), although the total number of ED visits or acute hospital admissions per patient in the year before and after medication review did not differ.

Conclusion A multifaceted medication review performed in the outpatient clinic reduced the number of potentially medication-related emergency department visits and could therefore reduce negative health outcomes and healthcare costs.