Eucalyptus Oils Phytochemical Composition in Correlation with Their Newly Explored Anti-SARS-CoV-2 Potential: in Vitro and in Silico Approaches

• DOI: 10.1007/s11130-024-01159-w
• Publication Date: 2024-03-16T12:01:33Z
• Authors: Riham A. El-Shiekh; Mona M. Okba; Asmaa A. Mandour; Omnia Kutkat; Rana Elshimy; Hany A. Nagaty; Rehab M. Ashour
• Keywords: Phytochemical

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the latest arisen contagious pathogen related to global outbreak of atypical pneumonia pandemic (COVID-19). The essential oils (EOs) Eucalyptus camaldulensis, E. ficifolia F. Muell., citriodora Hook, globulus Labill, sideroxylon Cunn. ex Woolls, and torquata Luehm. were investigated for its antiviral activity against SARS-CoV-2. EOs phytochemical composition was determined using GC/MS analysis. Correlation with explored also studied multi-variate data analysis Pearson's correlation. MTT cytopathic effect inhibition assays revealed very potent promising anti SARS-CoV-2 potential EO (IC