Cardiff cardiac ablation patient-reported outcome measure (C-CAP): validation of a new questionnaire set for patients undergoing catheter ablation for cardiac arrhythmias in the UK

• DOI: 10.1007/s11136-015-1194-1
• Publication Date: 2015-12-10T12:50:19Z
• Authors: Judith White; Kathleen L. Withers; Mauro Lencioni; Grace Carolan-Rees; Antony R. Wilkes; Kathryn A. Wood; Hannah Patrick; David Cunningham; Michael Griffith
• Keywords: Prom; Patient-reported outcome

To formally test and validate a patient-reported outcome measure (PROM) for patients with cardiac arrhythmias undergoing catheter ablation procedures in the UK [Cardiff Cardiac Ablation PROM (C-CAP)]. A multicentre, prospective, observational cohort study consecutive patient enrolment from three sites was conducted. Patients were sent C-CAP questionnaires before after an procedure. Pre-ablation C-CAP1 (17 items) comprised four domains: expectations; condition symptoms; restricted activity healthcare visits; medication general health. Post-ablation C-CAP2 (19 five domains including change symptoms procedural complications. Both also included generic EQ-5D-5L tool (EuroQol). Reliability, validity, responsiveness measures calculated. total of 517 valid pre-ablation 434 post-ablation responses received; showed good feasibility item acceptability. Internal consistency (Cronbach’s alpha >0.7) test–retest reliability acceptable all scales. scales high (effect size >0.8). improved significantly (p < 0.001) following across disease-specific global Minimal clinically important difference Improvement beyond smallest detectable 9 points (symptom severity scale), 3 (frequency duration 8 (impact on life scale) indicates change. Amendments to identified through validation process made produce final tools. The are valid, reliable, responsive tools measuring symptom change, impact, expectations arrhythmias. provide explore how impact upon patients’ lives.