Body composition and changes in health-related quality of life in older age: a 10-year follow-up of the Helsinki Birth Cohort Study

• DOI: 10.1007/s11136-020-02453-1
• Publication Date: 2020-03-02T19:02:47Z
• Authors: Tuija M. Mikkola; Hannu Kautiainen; Mikaela B. von Bo...; Minna K. Salonen; Niko Wasenius; Eero Kajantie; Johan G. Eriksson
• Keywords: Bioelectrical Impedance Analysis; Vitality; Mass index

Most studies examining the associations between body composition and health-related quality of life (HRQoL) in older age have been cross-sectional analyzed only fat or lean mass. Hence, it is poorly known whether mass are independently associated with subsequent changes HRQoL. We investigated baseline HRQoL over a 10-year period adults.We studied 1044 men women from Helsinki Birth Cohort Study (age 57-70 years at baseline). Bioelectrical impedance analysis was used to derive index (FMI, mass/height2) (lean mass/height2), dichotomized sex-specific medians. assessed using RAND 36-item Health Survey follow-up 10 later.When controlled for adjusted potential confounders, high FMI greater decline general health (standardized regression coefficient [β] = - 0.13, p 0.001), physical functioning (β 0.11, 0.002), role 0.003), vitality 0.08, 0.027), emotional 0.12, 0.007), component score 0.14, < 0.001). High also low all domains (β: 0.38 0.10). Lean not strongly change HRQoL.In community-dwelling adults, higher is, independent mass, lower Prevention adiposity may contribute preservation good age.