Synthesis and spectroscopic studies of some new oxazepine derivatives throughout [2+5] cycloaddition reactions (III)

• DOI: 10.1007/s11164-012-0877-2
• Publication Date: 2012-11-02T13:06:26Z
• Authors: Alaa J. Mahrath; Saadon A. Aowda; Sabah N. Kamil
• Keywords: 01 natural sciences; 0104 chemical sciences

The present work included condensation reactions of o-tolidine with different aromatic aldehydes in absolute ethanol to give Schiff bases (w 9 –w 12 ) in high yield which, on reaction with maleic and phthalic anhydride by [2+5] cycloaddition reactions in the presence of suitable solvents, give the corresponding [1,3]oxazepine-4,7-dione (w 9 m–w 12 m) and [1,3]oxazepine-1,5-dione (w 9 ph–w 12 ph), respectively. The structure of the newly synthesized compounds were monitored by TLC and established on the basis of elemental analysis, FT-IR, and 1H NMR.