Synthesis of tetrazolodiazepines by a five-centered four-component azide Ugi reaction. Scope and limitations

• DOI: 10.1007/s11172-012-0214-3
• Publication Date: 2013-07-05T07:25:49Z
• Authors: R. S. Borisov; A. I. Polyakov; L. A. Medvedeva; N. I. Guranova; L. G. Voskressensky
• Keywords: Sodium azide; Component (thermodynamics); Scope (computer science); Ammonium chloride

AbstractEfficient syntheses of tetrazolodiazepines are achieved by the title multicomponent reaction of aliphatic ketones, sodium azide, ammonium chloride, and isonitriles.