Synthesis of lupane triterpenoids with triphenylphosphonium substituents and studies of their antitumor activity
Betulinic acid
Terpene
Oleanane
DOI:
10.1007/s11172-013-0028-y
Publication Date:
2013-10-22T07:26:10Z
AUTHORS (12)
ABSTRACT
New derivatives of lupane triterpenoids, viz., 20,29-dihydrobetulinic and 3-epi-20,29-dihydrobetulinic acid derivatives containing triphenylphosphonium fragments as substituents were synthesized. These compound considerably exceed betulinic acid in antitumor activity.
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