Pharmacologically active hydrogels derived from silicon glycerolates and chitosan

• DOI: 10.1007/s11172-014-0578-7
• Publication Date: 2015-02-27T06:57:57Z
• Authors: E. Yu. Larchenko; T. G. Khonina; E. V. Shadrina; A. V. Pestov; O. N. Chupakhin; N. V. Menshutina; A. E. Lebedev; D. D. Lovskaya; L. P. Larionov; S. A. Chigvintsev
• Keywords: 02 engineering and technology; 0210 nano-technology

Novel hybrid chitosan-containing hydrogels were obtained from various functionalized silicon glycerolates by the sol—gel method. According to SEM images of aerogels prepared by supercritical drying in liquid CO2, chitosan serves as a template in the structuring of hybrid hydrogels. The hydrogels obtained are nontoxic, exhibit pronounced hemostatic activity, and are promising for medical use.